MARINI RENU CORRECTIVE HAND COMPLEX

Marini ReNu is an exciting new patent-pending, multi-functional solution shown to brighten overall skin tone and decrease the appearance of wrinkles, uneven texture, and discoloration on the hands.
With many advanced anti-ageing creams developed and marketed for the face, attention is now turning to other visible areas of the body. There is growing interest in creams for ageing skin on the hands, which receive high UV and environmental exposure. UV damage and secondary signs of ageing on the hands make them one of the most obvious indicators of age outside the face.
Photo-ageing
Photo-ageing is characterised by UV-induced epidermal and dermal changes, including textural changes, lentigines, actinic keratosis (AK) and seborrheic keratosis (SK).Dermal changes also play into visual ageing, including sagging and thinning of the skin, loss of elasticity, increased fine lines and wrinkles, and increased skin fragility.
Marini ReNu key ingredients
Marini ReNu Corrective Hand Complex contains multiple key ingredients designed to address the visible signs of UV damage and photo-aging, including: textural changes, increased hyperpigmentation and discoloration, increased fine lines and wrinkles and decreased elasticity.
Primarily, these ingredients include retinol, alpha-arbutin, kojic acid, azelaic acid, hexylresorcinol, licorice root extract, dipotassium glycyrrhizate and vitamin C as well as multiple antioxidants and soothing agents to help hydrate the skin, reduce irritation and protect against further damage.
Retinoids are vital to the maintenance of optimal skin health and studies have show that retinoids provide significant anti-aging benefits by increasing skin thickness and cellular turnover, promoting healthier skin.
Alpha-arbutin, licorice root extract, kojic dipalmitate, glycyrrhiza glabra, dipotassium glycyrrhizate (a component of licorice root extract) and hexylresorcinol all function to inhibit tyrosinase formation, thereby preventing initiation of the melanin production cycle.
Antioxidants vitamin C (ascorbyl palmitate) and vitamin E (tocopherol) plus multiple plant-based antioxidants help to further reduce irritation and decrease oxidative damage and hyperpigmentation secondary to UV exposure.
Physician study
29 subjects with Fitzpatrick skin type I-IV between the ages of 30-65 were enrolled in a study to evaluate Marini ReNu. To minimise the effect of seasonal sun exposure variation on lightening, participants in the four month study were enrolled from mid-December to late March in Omaha, Nebraska.
All subjects exhibited moderate sun-damage / photo-ageing on the backs of the hands, characterised by visible pigmentation, textural changes and fine lines and wrinkles.
Results
28 of the initial 29 subjects completed the study, There were zero adverse events and zero reported cases of skin irritation or acclimation. Improvement vs. baseline was statistically significant in all categories and time intervals for both right and left hands
The Marini ReNu Corrective Hand Complex was judged highly effective by both physician assessment and subject self-assessment in reducing the visible signs of UV damage and ageing, including loss of texture, wrinkles, pigmentation and loss of elasticity. Results were observed rapidly by both subjects and physicians, with statistically significant improvement noted at the very first follow-up visit after only 30 days of use.

1. Fisher GJ, Kang S, Varani J, et al. Mechanisms of photoaging and chronological skin aging. Arch. Dermatol. 2002 Nov. 138(11) 1462-70. 2. Kligman AM. Early Destructive Effect of Sunlight on Human Skin. JAMA.1969; 210(13):2377-2380. 3. Stefanaki C SAKA. Topical retinoids in the treatment of photoaging. J Cosmet Dermatol. 2005; June; 4(2). 4. Zhu W, Gao J. The use of Botanical Extracts as Topical Skin-Lightening Agents for the Improvement of Skin Pigmentation Disorders. Journal of Investigative Dermatology Symposium Proceedings. 2008; 13: 20-28.JAN MARINI SKIN RESEARCH Baseline and four months after treatment to refine texture and hyperpigmentation with Marini ReNu